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Intraoperative imaging of the brain macro- and microcirculation

Juan Zhou
Departments of Anesthesia, Pain Management and Perioperative Medicine, Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada
[Applied Cardiopulmonary Pathophysiology 16: 270-275, 2012]


Advances in imaging technology have provided new diagnostic methods for assessment of cerebral vascular perfusion and quantitative analysis of the microcirculation during cerebral surgery. In this article, a range of imaging procedures are described: Digital Subtraction Angiography (DSA) and Three-Dimensional Computed Tomography Angiography (3D-CTA), Indocyanine Green Video Angiography (ICGVA), Orthogonal Polarization Spectral (OPS) Imaging, Sidestream Dark-Field (SDF) Imaging, and Laser-Doppler Flowmetry (LDF).
All these measurements will foster development of precise evaluation tools for microcirculation-related microvascular conditions, e. g. stroke and hemorrhage, and support clinicians in their therapeutic decision-making process.

Key words: angiography, cerebral surgery, intraoperative imaging, microcirculation, macrocirculation

Corresponding author
Juan Zhou, MD, Ph.D
Assistant Professor, Departments of Anesthesia, Microbiology and Immunology
Dalhousie University
5850 College Street
6H Tupper Building
Halifax, NS, B3H 1X5
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